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THE RADIOLOGY OF LIGNAC‐FANCONI DISEASE
Author(s) -
ASTLEY R.,
TEALL C. G.,
BICKEL H.
Publication year - 1952
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.1952.tb16977.x
Subject(s) - rickets , medicine , fanconi syndrome , disease , malignant disease , radiography , dermatology , pediatrics , pathology , vitamin d and neurology , radiology , kidney , cancer
Summary The radiological findings in seven children with Lignac‐Fanconi disease are described and compared with those in the literature. Bone changes may be absent. When present, they are those of simple rickets or, in the more chronic cases, of long‐standing late rickets. The appearances are non‐specific and not distinguishable from those of avitaminosis‐D or from “resistant” rickets. These observations agree with theoretical conceptions because the bone changes, contrary to previous belief, probably originate in a failure of intestinal absorption of phosphorus and calcium. We wish to thank Prof. G. F anconi and Dr. H. B oehncke for sending us prints from the radiographs of their patients, and Prof. A. V. N eale for permitting us to use the X‐rays of Case 7.