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Plenary Session—Tuberculosis
Publication year - 1948
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.1948.tb16142.x
Subject(s) - medicine , vaccination , tuberculin , incidence (geometry) , tuberculosis , tuberculin test , pediatrics , bcg vaccine , age groups , immunology , demography , pathology , physics , sociology , optics
Summary 1 o ) Our experiences confirm the conclusions of most of the papers published up to the present, about the inocnity of BCG in the new born, and in the older non‐infected. 2 o ) The statistics of Córdoba (R. A.) were drawn out of a total of 22 254 vaccinated in the city, making a total of 28 132 including the vaccinated in the rest of the province. 3 o ) The vaccination was preferently done on new born, and in a. smaller number anions; older children. 4 o ) The following methods were used: oral, subcutaneous, multipuneture. scarification and intracutaneous. Most of the children were vaccinated with the last method in a dosis of 0.15 nig. 5 o ) The tuberculin test was done generally with 1 mg of OT, injected intracutaneonsly. From this, we gather that the incidence of reactors reaches 95 % of the intracutaneous vaccinated. 6 o ) The efficiency of the vaccination, is deduced from our comparative studies between vaccinated and non‐vaccinated, belonging to similar contact household. a) The tuberculin text showed milder response (one or two plus) in the vaccinated than in the infected non‐vaccinated (hyperergic). b) The changes in the X‐Ray films, studied in 2 groups of 112 children each, both between the ages of 2 and 10 years, one group vaccinated at birth, and the other non‐vaccinated showed: Among exposed vaccinated, 57.5%, of lesions, and in exposed non‐vaccinated 74.3 %,. Among non exposed, the incidence of lesions. was 18.9%, in the vaccinated, and 47.6 %, in the non‐vaccinated. Tins favorable difference in vaccinated children, is not only numerical but it is also less significative in the anal anatomo‐radiological changes shown by the film. 7 o ) The investigation of tubercle bacilli in the stomach contents, made in 20 vaccinated and 20 non‐vaccinated children, both with household contact and with changes in the X‐Ray films, showed positive result in 10 o ;, of the vaccinated, and ‐45 o ., of non‐vaccinated. 8 o ) In the Latin American Countries, where the first‐infection problem not only deals with the child but also with the young adult in a high proportion (50%), there is a. need of vaccination in a large scale, while the assistance resources are not enough to control all the open cases. 9 o ) We therefore come to the conclusion that a‐ Committee or Laboratory is needed which would centralize the investigation, in order to uniform the preparation of the vaccine and the method of its use, with the purpose of obtaining results which could be compared.