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A Simple Micro‐Method for Studying the Retraction of the Blood Clot
Author(s) -
LEVANDERLINDGREN MAJ
Publication year - 1948
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.1948.tb03746.x
Subject(s) - medicine , clot retraction , significant difference , coefficient of variation , normal values , mean value , surgery , chromatography , platelet , mathematics , platelet aggregation , statistics , chemistry
SUMMARY 1. A new simple micromethod for studying the clot retraction is described in which the coagulum is allowed to form around a horse‐hair that is withdrawn with the adherent clot, after which the residual expressed serum is measured and the retraction evaluated. 2. 222 double determinations performed on patients with normal blood gave an average difference of 2.3 per cent with a deviation range of ± 3.2 per cent which with an average value 52.6 for the retraction gives a variation coefficient of ± 6.0 per cent for the method. 3. A comparison between the 2–hour and the 24–hour values showed that the latter are on an average somewhat higher, but the difference was not significant. 4. Time studies of the retraction of capillary and vcnous blood showed that retraction in normal cases is complete after 120 but not after 90 minutes. 5. In four cases of thrombocytopenia the method showed reduced retraction after two hours and as a rule also after 24 hours. The values were more irregular than in the normal series.