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Treatment of Pyloric Stenosis in Infants with Methylscopolamine Nitrate
Author(s) -
ELGENMARK OLLE
Publication year - 1945
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.1945.tb16831.x
Subject(s) - medicine , vomiting , pyloric stenosis , pylorus , stenosis , stomach , anesthesia , pediatrics , nitrate , surgery , ecology , biology
Summary. Methylscopolamine nitrate has proved to be a superior antispasmodic in internal medicine, and it therefore seemed likely that it might be equally valuable in pediatric practice, in particular in the treatment of infantile pyloric stenosis. In 6 of the 9 patients treated immediate cessation of the vomiting, improvement in the general condition, and a gain in weight was achieved. Three patients did not respond to the treatment and an operation was necessary. The most striking feature was the rapidity with which the effect occurred. In many of the infants it occurred on the same day as the first dose, and in any case an improvement was noted within a few days. Another quality of this drug which makes it especially suitable for use in children is its harmlessness. Not even after a long period of medication were any by‐effects to be observed, other than a sudden flush which rapidly subsided The drug has also been tried and proved to be very effective in the treatment of other forms of vomiting occurring in infancy.