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Escalating therapy of cutaneous side effects of EGFR inhibitors: experience of German reference centers
Author(s) -
Homey Bernhard,
Gerber Peter Arne,
Wollenberg Andreas,
Dirschka Thomas,
Hassel Jessica C,
Bölke Edwin,
Hauschild Axel,
Gutzmer Ralf
Publication year - 2012
Publication title -
jddg: journal der deutschen dermatologischen gesellschaft
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.463
H-Index - 60
eISSN - 1610-0387
pISSN - 1610-0379
DOI - 10.1111/j.1610-0387.2012.07948.x
Subject(s) - german , medicine , context (archaeology) , adverse effect , medline , intensive care medicine , pharmacology , history , paleontology , archaeology , political science , law , biology
Summary Recommendations for the management of cutaneous adverse effects of inhibitors of the epidermal growth factor receptor (EGFR) are urgently needed. In this context an expert panel of German dermatologists recently proposed a 3‐step management concept based on personal experience and a current literature consensus. While steps 1 and 2 addressed general and preventive measures, as well as the therapy that can be performed by the primary treating physician, here we address the management of challenging cases (step 3) that do not respond well to basic measures and should be referred to an experienced dermatologist.