Premium
Update on in vitro allergy diagnostics
Author(s) -
Treudler Regina
Publication year - 2012
Publication title -
jddg: journal der deutschen dermatologischen gesellschaft
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.463
H-Index - 60
eISSN - 1610-0387
pISSN - 1610-0379
DOI - 10.1111/j.1610-0387.2011.07860.x
Subject(s) - allergy , dander , sensitization , plant lipid transfer proteins , medicine , food allergy , immunology , respiratory allergy , allergen , immunoglobulin e , biology , biochemistry , antibody , gene
Summary Component‐resolved diagnostics (CRD) have become of growing importance in clinical investigation of IgE‐mediated allergies. This review updates the current use of CRD in respiratory allergies (e. g. to pollen, animal dander, mites, latex), as well as in allergies to hymenoptera venom or in food allergies to plants (e. g. Bet v 1 homologues, lipid transfer proteins, storage proteins) or to animal‐derived food allergens (e. g. milk, meat, fish). CRD may help to elucidate the clinical relevance of an allergic sensitization. In some cases, CRD may also be useful in predicting either severity of clinical reactions or the therapeutic effect of specific immunotherapy.