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Desquamative gingivitis as a manifestation of chronic mucocutaneous disease
Author(s) -
Gagari Eleni,
Damoulis Petros D.
Publication year - 2011
Publication title -
jddg: journal der deutschen dermatologischen gesellschaft
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.463
H-Index - 60
eISSN - 1610-0387
pISSN - 1610-0379
DOI - 10.1111/j.1610-0387.2010.07543.x
Subject(s) - mucocutaneous zone , cicatricial pemphigoid , medicine , pemphigus vulgaris , gingivitis , dermatology , disease , physical examination , oral mucosa , biopsy , pathology , pemphigoid , dentistry , bullous pemphigoid , immunology , surgery , antibody
Summary Desquamative gingivitis (DG) is a clinical descriptive term indicating “peeling gums”. DG is usually the result of a disease process that causes separation of the epithelium from the underlying connective tissue in the oral masticatory mucosa. DG may be a manifestation of several mucocutaneous diseases, most commonly cicatricial pemphigoid, pemphigus vulgaris and lichen planus. Correct diagnosis of the underlying disease in DG patients requires careful clinical observation, detailed examination of medical history, biopsy and histopathological examination of the lesions as well as more specialized tests such as direct and indirect immunofluorescence. Treatment of DG consists of treating the underlying disease and often requires the use of immunosuppressive agents, such as corticosteroids. Elimination of local gingival irritants, such as dental plaque and calculus, can significantly improve the treatment outcome.