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Cutaneous macroglobulinosis deposits in a patient with IgM paraproteinemia/incipient Waldenström macroglobulinemia
Author(s) -
Lüftl Matthias,
SauterJenne Birthe,
Gramatzki Martin,
Eckert Fritjof,
Jenne Lars
Publication year - 2010
Publication title -
jddg: journal der deutschen dermatologischen gesellschaft
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.463
H-Index - 60
eISSN - 1610-0387
pISSN - 1610-0379
DOI - 10.1111/j.1610-0387.2010.07392.x
Subject(s) - paraproteinemia , macroglobulinemia , medicine , waldenstrom macroglobulinemia , paraproteinemias , dermatology , pathology , differential diagnosis , lymphoplasmacytic lymphoma , immunoglobulin m , gammopathy , multiple myeloma , monoclonal , immunoglobulin g , immunology , antigen , antibody , lymphoma , monoclonal antibody
Summary A 43‐year‐old healthy patient developed disseminated flat skin‐colored to red‐brown papules over a few months. These papules were the result of cutaneous IgM deposits representing the first symptom of a hitherto undiagnosed IgM paraproteinemia. This extremely rare skin manifestation of IgM paraproteinemia e. g. possibly incipient Waldenström macroglobulinemia should be included in the histopathological differential of eosinophilic dermal deposits.