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De novo tuberculosis during infliximab therapy in a patient with Behçet disease
Author(s) -
Skvara Hans,
Duschek Nikolaus,
Karlhofer Franz
Publication year - 2009
Publication title -
jddg: journal der deutschen dermatologischen gesellschaft
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.463
H-Index - 60
eISSN - 1610-0387
pISSN - 1610-0379
DOI - 10.1111/j.1610-0387.2009.07040.x
Subject(s) - medicine , tuberculosis , miliary tuberculosis , infliximab , latent tuberculosis , behcet's disease , fulminant , disease , mycobacterium tuberculosis , dermatology , surgery , pathology
Summary A woman with oculocutaneous Behçet disease developed primary tuberculosis while being treated with infliximab. A latent tuberculosis infection had been excluded before therapy. After more than 80 weeks of treatment, the patient complained of fevers, night sweats, shivering and vigorous cough. The chest x‐ray showed miliary shadowing. Mycobacterium tuberculosis was identified. The history revealed recent contact to an individual with smear‐positive tuberculosis. This constellation speaks in favor of a de novo tuberculosis infection with a fulminant course.