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Cutaneous infection with Leishmania infantum in an infant treated successfully with miltefosine
Author(s) -
Neub Angela,
Krahl Dieter,
Stich August,
Amon Ulrich
Publication year - 2008
Publication title -
jddg: journal der deutschen dermatologischen gesellschaft
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.463
H-Index - 60
eISSN - 1610-0387
pISSN - 1610-0379
DOI - 10.1111/j.1610-0387.2008.06779.x
Subject(s) - miltefosine , leishmania infantum , medicine , nodule (geology) , dermatology , serology , leishmania , leishmaniasis , pathology , biology , visceral leishmaniasis , parasite hosting , immunology , paleontology , antibody , world wide web , computer science
Summary A two‐year‐old girl presented with a 20 month history of a facial nodule which had appeared after a vacation on Mallorca. Various topical treatments at other hospitals for the working diagnosis of mastocytoma failed to prevent a slow increase in size and the onset of systemic signs and symptoms. An indurated crusted nodule evolved. Histology, tissue PCR and serologic analysis proved the presence of Leishmania infantum. She was treated with oral miltefosine 10 mg p.o. t.i.d. for 28 days. Regression was apparent after 8 weeks and complete healing after 6 months.