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Herpes simplex vegetans: atypical genital herpes infection with prominent plasma cell infiltration in B‐cell chronic lymphocytic leukemia
Author(s) -
Römer Annette,
Greiner Axel,
Enk Alexander,
Hartschuh Wolfgang
Publication year - 2008
Publication title -
jddg: journal der deutschen dermatologischen gesellschaft
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.463
H-Index - 60
eISSN - 1610-0387
pISSN - 1610-0379
DOI - 10.1111/j.1610-0387.2008.06736.x
Subject(s) - medicine , herpes simplex virus , infiltration (hvac) , pathology , leukemia , chronic lymphocytic leukemia , simplexvirus , plasma cell , hyperplasia , virus , immunology , viral disease , herpesviridae , bone marrow , physics , thermodynamics
Summary Herpes simplex vegetans is a rare disorder even in immunocompromised patients. It typically affects patients with HIV or myeloproliferative diseases.The atypical cutaneous lesions show papillomatous vegetations in varying locations. Histologically the lesions show pseudoepitheliomatous hyperplasia of squamous epithelium, plasma cell infiltration and are positive for HSV 1 and/or HSV 2. Herpes simplex vegetans often responds poorly to treatment in immunocom‐promised patients.