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Light chain multiple myeloma with cutaneous AL amyloidosis
Author(s) -
Becker Maria Rita,
Rompel Rainer,
Plum Jörg,
Gaiser Timo
Publication year - 2008
Publication title -
jddg: journal der deutschen dermatologischen gesellschaft
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.463
H-Index - 60
eISSN - 1610-0387
pISSN - 1610-0379
DOI - 10.1111/j.1610-0387.2008.06617.x
Subject(s) - macroglossia , multiple myeloma , amyloidosis , medicine , pathology , congo red , al amyloidosis , stain , dermatology , immunoglobulin light chain , complication , amyloid (mycology) , staining , tongue , surgery , chemistry , immunology , antibody , adsorption , organic chemistry
Summary Cutaneous AL amyloidosis is one complication of multiple myeloma. In our patient, painful sclerotic skin changes on the extremities and macroglossia were the presenting features which led to a more detailed investigation and the diagnosis of multiple myeloma. Histological examination revealed cutaneous deposits of amyloid which were positive with Congo red stain and had an apple green color in polarized light.