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Late onset of a facial variant of steatocystoma multiplex – Calretinin as a specific marker of the follicular companion cell layer
Author(s) -
Riedel Christian,
Brinkmeier Thomas,
Kutzner Heinz,
Plewig Gerd,
Frosch Peter J.
Publication year - 2008
Publication title -
jddg: journal der deutschen dermatologischen gesellschaft
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.463
H-Index - 60
eISSN - 1610-0387
pISSN - 1610-0379
DOI - 10.1111/j.1610-0387.2007.06603.x
Subject(s) - pathology , calretinin , immunohistochemistry , histology , medicine , anatomy , biology
Summary Steatocystoma multiplex is a rare, almost exclusively autosomal dominant disease of the sebaceous glands. The sites of predilection are the sternal region, upper back, axillae and proximal parts of the extremities. A 78‐year‐old woman developed multiple yellowish nodules only on the face over a few months. Histology revealed large cysts with a thin wall and connection to sebaceous glands. Immunohistochemical analysis showed the inner epithelial layer of the cysts was positive with calre‐tinin. With curettage and CO2 laser therapy, a good cosmetic result was achieved. This is the first case report in the German literature of a rare sporadic form of steatocystoma multiplex with late onset and exclusive localization in the face.