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Intralesional therapy of metastatic spreading melanoma with beta‐interferon
Author(s) -
Rapprich Harriet,
Hagedorn Manfred
Publication year - 2006
Publication title -
jddg: journal der deutschen dermatologischen gesellschaft
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.463
H-Index - 60
eISSN - 1610-0387
pISSN - 1610-0379
DOI - 10.1111/j.1610-0387.2006.06054.x
Subject(s) - dacarbazine , medicine , melanoma , radiation therapy , cheek , alpha interferon , surgery , dermatology , chemotherapy , metastatic melanoma , interferon , immunotherapy , interferon beta , interferon α , oncology , cancer , cancer research , immunology
Summary A 74‐year‐old female patient developed multiple local metastases after excision of a nodular melanoma of the left cheek. There was no regression after treatment with dacarbazine (DTIC ® ) and radiotherapy. After treatment with intralesional interferon‐β, the metastases regressed completely. The dosage was 5 million IU interferon‐β (Fiblaferon ® ) three times weekly with courses of two and four weeks, separated by a month. Except for local swelling and inflammation, no side effects occurred. Five years after completing therapy, the patient is still tumor‐free.