Open AccessStillborns, partially monosomic and partially trisomic, in the offspring of a boar carrying a translocation: rcp(14;15)(q29;q24)
Author(s) -
GUSTAVSSON INGEMAR,
JONSSON LENNART
Publication year - 1992
Publication title -
hereditas
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.819
H-Index - 50
eISSN - 1601-5223
pISSN - 0018-0661
DOI - 10.1111/j.1601-5223.1992.tb00004.x
Subject(s) - chromosomal translocation , biology , boar , offspring , proband , sire , andrology , genetics , chromosome , mating , pronucleus , karyotype , robertsonian translocation , zygote , embryo , pregnancy , sperm , zoology , embryogenesis , gene , medicine , mutation
Smaller litters and an increased rate of stillbirth were observed among the offspring of a boar carrying a reciprocal translocation, rcp(14;15)(q29;q24). The translocation appeared to be of de novo origin since, according to the owner, the sire and dam of the proband boar both produced normal‐sized litters and no stillbirths. The increased rate of stillbirth among offspring of the proband was due to the production of zygotes partially monosomic for chromosome 14 (14q29‐qter) and partially trisomic for chromosome 15 (15q24 ‐qter). Three out of 4 such stillborn piglets had a cleft palate. One of the 4 also had a cardiac septal defect. Two partially monosomic and partially trisomic foetuses recovered at 95 days' pregnancy appeared patho‐anatomically normal. The smaller litters were assumed to be due to an early wastage of embryos having other types of unbalanced karyotypes caused by the reciprocal translocation.