Open AccessSemi‐automatic karyotyping facility‐a clinical test
Author(s) -
WULF HANS CHRISTIAN,
PHILIP JOHN
Publication year - 1986
Publication title -
hereditas
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.819
H-Index - 50
eISSN - 1601-5223
pISSN - 0018-0661
DOI - 10.1111/j.1601-5223.1986.tb00638.x
Subject(s) - karyotype , biology , chromosome analysis , chromosome , andrology , genetics , medicine , gene
A semiautomatic karyotyping system without pattern recognition facilities, taking advantage of the skill of cytotechnicians to classifying the chromosomes but automating the production of the karyotype on a polaroid film, has been tested in clinical practice. Under “competitive” circumstances a total analysis of amniotic cells took 38 min and the corresponding manual analysis 97 min. The time used for the analysis of lymphocytes were 35 min and 93 min respectively. The variation in analysis time for the three technicians was less than 15%. The time consumption for a chromosome analysis of amniotic cells in daily routine has been estimated to about 3 hours.