Open AccessCytogenetic studies in non‐Hodgkin lymphomas‐Results from fineneedle aspiration samples
Author(s) -
KRISTOFFERSSON ULF,
OLSSON HÅKAN,
ÅKERMAN MÅNS,
MITELMAN FELIX
Publication year - 1985
Publication title -
hereditas
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.819
H-Index - 50
eISSN - 1601-5223
pISSN - 0018-0661
DOI - 10.1111/j.1601-5223.1985.tb00484.x
Subject(s) - biology , fine needle aspiration , cytogenetics , chromosome , lymphoma , oncology , medicine , immunology , genetics , biopsy , gene
118 samples obtained by means of fine‐needle aspiration from 86 cases of non‐Hodgkin, non‐Burkitt lymphomas have been investigated cytogenetically with chromosome banding technique. If>5 times 10 6 cells were obtained at aspiration the success rate with the technique used was almost 70%, while if the number of cells was lower it was only about 15%. Technical aspects, and detailed cytogenetic findings in 48 successful cases, are reported. There was no difference in success rate due to tumor stage, or sampling at diagnosis or in relapse. It is concluded that the fine‐needle aspiration technique has certain advantages in cancer cytogenetics; it is easy to handle, requires no surgical intervention, causes little distress to the patient, and the success rate is acceptable.