Open AccessThalassaemia and haptoglobin polymorphism in Egypt
Author(s) -
HABIB ZACHARIAS
Publication year - 1982
Publication title -
hereditas
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.819
H-Index - 50
eISSN - 1601-5223
pISSN - 0018-0661
DOI - 10.1111/j.1601-5223.1982.tb00864.x
Subject(s) - haptoglobin , biology , heterozygote advantage , polymorphism (computer science) , genetics , allele frequency , population , gene , allele , immunology , demography , sociology
The determination of serum haptoglobin types and their distribution in 505 “genuine” unrelated Egyptians revealed a Hp 1 gene frequency of 0.34, a Hp 2 gene frequency of 0.66 and a slightly higher prevalence of Hp 2‐2 than of Hp 2‐1. Ahaptoglobinaemia was present in 0.40 % of the examined individuals. There were no significant differences between males and females. There were 33 thalassaemia heterozygotes in the sample and these individuals were not at variance with the remainder of the sample population in respect of their serum haptoglobins.