Open AccessProphase analysis of ring chromosome 13—an attempt at phenotypekaryotype correlation
Author(s) -
LAGERGREN MARIANNE,
BÖRJESON MATS,
MITELMAN FELIX
Publication year - 1980
Publication title -
hereditas
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.819
H-Index - 50
eISSN - 1601-5223
pISSN - 0018-0661
DOI - 10.1111/j.1601-5223.1980.tb01363.x
Subject(s) - prometaphase , biology , ring chromosome , prophase , karyotype , mitosis , chromosome , breakpoint , genetics , ring (chemistry) , cytogenetics , meiosis , chemistry , organic chemistry , gene
A patient with a ring chromosome 13 is presented and compared with previously reported cases analyzed by banding techniques. The patient displayed many of the clinical stigmata characteristic of the ring 13 syndrome. By analyses of early mitotic stages (prometaphase and late prophase chromosomes), the breakpoint on the long arm of chromosome 13 was tentatively localized to band q33, and an attempt at phenotype‐karyotype correlation was made.