Open AccessEffects of superoxide dismutase and catalase on radiation‐induced chromosome aberrations: Dose and cell cycle dependence
Author(s) -
NORDENSON INGRID
Publication year - 1978
Publication title -
hereditas
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.819
H-Index - 50
eISSN - 1601-5223
pISSN - 0018-0661
DOI - 10.1111/j.1601-5223.1978.tb01271.x
Subject(s) - superoxide dismutase , catalase , enzyme , chromosome , biology , irradiation , microbiology and biotechnology , biochemistry , gene , physics , nuclear physics
The frequency of chromosome aberrations induced by radiation in G 0 and G 2 was significantly reduced by adding the enzymes superoxide dismutase and/or catalase to lymphocytes either before or after their irradiation. A concentration of 5 times 10 ‐2 mg enzyme/ml medium had a maximal effect. Heat‐inactivated enzymes had no effect, nor had Cu 2+ ‐ions.