Open AccessEnhancement by caffeine of cell killing and chromosome damage in Chinese hamster cells treated with thiotepa
Author(s) -
STURELID S.
Publication year - 1977
Publication title -
hereditas
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.819
H-Index - 50
eISSN - 1601-5223
pISSN - 0018-0661
DOI - 10.1111/j.1601-5223.1977.tb01393.x
Subject(s) - chinese hamster , thiotepa , biology , caffeine , chromosome , hamster , cell , genetics , microbiology and biotechnology , cell culture , chemotherapy , endocrinology , gene , cyclophosphamide
Chinese hamster cells were treated with thiotepa and subsequently grown in the presence of 0.5 mM caffeine. The effect was analysed with respect to chromosome damage and cell killing. Post‐treatments with caffeine had a strong potentiating effect on both phenomena.