Open AccessIn vitro induction of G bands and uncoiling with fucidin
Author(s) -
SANDERMANN JES,
RØNNE MOGENS
Publication year - 1977
Publication title -
hereditas
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.819
H-Index - 50
eISSN - 1601-5223
pISSN - 0018-0661
DOI - 10.1111/j.1601-5223.1977.tb01244.x
Subject(s) - cycloheximide , metaphase , in vitro , biology , microbiology and biotechnology , biochemistry , chromosome , protein biosynthesis , gene
When added in low concentration to lymphoid G 2 phase cells, fucidin induces banding or uncoiling in the metaphase chromosomes. The bands are found to be G bands. The uncoiling is similar to the uncoiling observed after daunomycin or cycloheximide treatment of lymphoid G 2 phase cells. The possible mechanism behind this in vitro induction is discussed.