Open AccessDistribution of break points in reciprocal translocations in children ascertained in population studies
Author(s) -
NIELSEN J.,
RASMUSSEN K.
Publication year - 1976
Publication title -
hereditas
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.819
H-Index - 50
eISSN - 1601-5223
pISSN - 0018-0661
DOI - 10.1111/j.1601-5223.1976.tb01541.x
Subject(s) - reciprocal , chromosomal translocation , biology , population , distribution (mathematics) , chromosome , genetics , mathematics , demography , gene , mathematical analysis , sociology , philosophy , linguistics
Analysis of the distribution of break points in autosomal reciprocal translocations has been made in 43 newborn children found in population studies. The distrubution was random as far as chromosome number, terminal, median or centromeric localization are concerned, but non‐random as far as localization according to Q‐positive and Q‐negative bands is concerned, with a significant increase in the frequency of break points localized in Q‐negative bands compared with Q‐positive bands. The results have been compared with previous investigations of break points in families with selected ascertainment and induced break points in in‐vitro studies.