Open AccessA cytological view of the functional organization of chromomeres
Author(s) -
SORSA VEIKKO
Publication year - 1976
Publication title -
hereditas
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.819
H-Index - 50
eISSN - 1601-5223
pISSN - 0018-0661
DOI - 10.1111/j.1601-5223.1976.tb01539.x
Subject(s) - biology , gene , dna , genetics , messenger rna , rna , chromosome , evolutionary biology , microbiology and biotechnology
Models for genetic regulation and functional organization of eukaryotic chromosomes as well as experimental data on the structural organization of chromosomal DNA and RNA units. are compared with recent results of electron‐microscopic studies on chromomeres and cytogenetic localization of genes. The concept that the structural genes of genetic units are located at the end of chromomeric loops seems to be consistent with most cytological and biochemical data, and is also in accordance with hypotheses for the evolution of chromomeric DNA units. The concept implies that the messenger unit is located near the 5′ end in the total transcript of a chromomere. The RNA‐segments synthesized after the messenger unit may have regulative functions on other genetic units.