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Timing of temperature‐sensitive period for lethality of Abruptex mutations of Drosophila melanogaster
Author(s) -
Portin Petter,
Sirén Marhtta
Publication year - 1976
Publication title -
hereditas
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.819
H-Index - 50
eISSN - 1601-5223
pISSN - 0018-0661
DOI - 10.1111/j.1601-5223.1976.tb01199.x
Subject(s) - biology , drosophila melanogaster , heterozygote advantage , complementation , allele , genetics , genotype , mutation , lethality , period (music) , microbiology and biotechnology , phenotype , gene , physics , acoustics
Of the Abruptex ( Ax , 1–3.0) mutations of Drosophika melanogaster the Ax 28 allele is a temperature‐sensitive lethal. The mutation is viable at 25°C but nearly lethal at 29°C. Also the interaction of Ax 28 and Ax E2 alleles is temperature‐sensitive. The heterozygous genotype Ax 28 /Ax E2 is semilethal at 25°C but lethal at 29°C. The decreased viability of the heterozygote is caused by the negative complementation of the alleles involved. The temperature‐sensitive period of both homozygous Ax 28 and heterozygous Ax 28 /Ax E2 genotypes is monophaseous, occurring in the beginning of the pupal stage in the first case, and in the end of the third larval instar and beginning of the pupal stage in the latter case.

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