Open AccessCharacterization of a meiotic control gene affecting recombination in Drosophila melanogaster
Author(s) -
VALENTIN JACK
Publication year - 1973
Publication title -
hereditas
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.819
H-Index - 50
eISSN - 1601-5223
pISSN - 0018-0661
DOI - 10.1111/j.1601-5223.1973.tb01137.x
Subject(s) - recombination , biology , genetics , ectopic recombination , meiosis , nondisjunction , drosophila melanogaster , autosome , genetic recombination , x chromosome , chromosome , centromere , gene , mitotic crossover , aneuploidy
In Drosophila melanogaster the recessive 3rd chromosome gene, mei‐1 , reduces recombination in the region around ct (target region) in the X chromosome drastically. Other regions show less extreme reductions or increased recombination (centromere region). Totally, recombination frequency in X is halved. Recombination in autosomes is little affected by mei‐1. Coincidence appears unaffected by mei‐1 , at least in X. Nondisjunction of X's in females is trebled by mei‐1. — Interchromosomal effects of the Cy inversions increase recombination in X. In the target region, the effects of Cy and of mei‐1 are additive. Both X‐rays and EMS reduce recombination in this region. The reduction is additive to mei‐1 effects. According to S andler et al. (1968) genes changing recombination but not coincidence probably affect the exchange process rather than its preconditions. However this need not be the case for each such gene. By analogy to probability, different factors with additive effects on a phenomenon are likely to affect the same process. In the target region, mei‐1, Cy , X‐rays and EMS may therefore all affect the same process, presumably chromosome pairing.