Open AccessA bibliography of literature concerning chromosome identification ‐ with special reference to fluorescence Giemsa staining techniques
Author(s) -
NILSSON BIRGIT
Publication year - 1973
Publication title -
hereditas
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.819
H-Index - 50
eISSN - 1601-5223
pISSN - 0018-0661
DOI - 10.1111/j.1601-5223.1973.tb01088.x
Subject(s) - biology , giemsa stain , chromosome , genetics , identification (biology) , staining , cytogenetics , karyotype , computational biology , g banding , microbiology and biotechnology , gene , botany
During the last five years the techniques for detailed analysis of chromosome differences have developed very rapidly. Each chromosome of a species can now be often identified by its specific banding sequence. This leads to an increased precision in the recognition of chromosomal aberrations, mapping of structural rearrangements and detection of polymorphic variations, all of which can be usefully applied in biology and medicine. The technique introduced by C aspersson et al. (1968), i.e., using the intense fluorescence obtained at specific chromosome regions after staining with quinacrine derivatives for the purpose of recognizing the chromosomes, has become an exceedingly useful tool in cytogenetics.