Open AccessCOMPARATIVE IDIOGRAM ANALYSIS OF THE RAT AND THE YOSHIDA RAT SARCOMA
Author(s) -
TJIO JOE HIN,
LEVAN ALBERT
Publication year - 1956
Publication title -
hereditas
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.819
H-Index - 50
eISSN - 1601-5223
pISSN - 0018-0661
DOI - 10.1111/j.1601-5223.1956.tb03017.x
Subject(s) - cancer genetics , chromosome , biology , humanities , genetics , library science , philosophy , cancer , computer science , gene
17 Pags.- 3 Tabls.- 4 Figs.Complete idiogram analyses were made for ten spermatogonial metaphases\udof the rat and ten stemline metaphases of the Yoshida sarcoma.\udIn Fig. 3 these analyses are summarized as two average idiograms. The\udevolution of the tumour idiogram cannot have taken place only by new combinations\udof unchanged chromosome arms. A great number of\udstructural rearrangements, also involving smaller units, must be assumed.\udThe morphologic identity within the originally homologous\udchromosome pairs has been totally blurred during the development of\udthe tumour.\udThe sex chromosomes of the rat have been followed during mitosis\udand meiosis. Both X and Y are heteropycnotic during the first meiotic\uddivision. only the Y shows heteropycnosis in spermatogonial mitoses;\udneither of them is clearly heteropycnotic in liver mitoses. The Y was \udidentified as the smallest rod chromosome present. The X is one of the\udlarger medium-sized rods, probably number five in size order counted\udfrom the longest rod.Peer reviewe