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The influence of a hydrogen peroxide and glycerol containing mouthrinse on plaque accumulation: a 3‐day non‐brushing model
Author(s) -
Hoenderdos NL,
Rosema NAM,
Slot DE,
Timmerman MF,
Van Der Velden U,
Van Der Weijden GA
Publication year - 2009
Publication title -
international journal of dental hygiene
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.674
H-Index - 38
eISSN - 1601-5037
pISSN - 1601-5029
DOI - 10.1111/j.1601-5037.2009.00367.x
Subject(s) - medicine , hydrogen peroxide , glycerol , dentistry , tooth brushing , biochemistry , toothbrush , composite material , brush , materials science , chemistry
Aim: To evaluate the inhibition of plaque growth by an experimental mouthrinse (BioXyl ® ) based on hydrogen peroxide/glycerol. Design: It was a double‐blind, randomized study involving 40 volunteers in good general health. At the start of the trial, all participants received a dental prophylaxis to remove all plaque deposits. During the next 3 days subjects refrained from any mechanical oral hygiene procedure, except for the allocated mouthrinse being either the hydrogen peroxide (H 2 O 2 ; 0.013% H 2 O 2 /0.004% glycerol) or the placebo without H 2 O 2 . At the third day of appointment, plaque levels were assessed at six sites per tooth. Results: The test group had a mean overall plaque score of 2.66 and the placebo group of 2.70. The difference in plaque scores between the two groups was not statistically significant. Conclusions: The results of this pilot study showed that there was no statistically significant difference between the H 2 O 2 /glycerol group and the placebo group with respect to plaque inhibition within this study design.