Open AccessApoE isoform‐dependent deficits in extinction of contextual fear conditioning
Author(s) -
Olsen R. H. J.,
Agam M.,
Davis M. J.,
Raber J.
Publication year - 2012
Publication title -
genes, brain and behavior
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 1.315
H-Index - 91
eISSN - 1601-183X
pISSN - 1601-1848
DOI - 10.1111/j.1601-183x.2012.00833.x
Subject(s) - extinction (optical mineralogy) , psychology , context (archaeology) , apolipoprotein e , cognition , fear conditioning , neuroscience , freezing behavior , conditioning , disease , developmental psychology , medicine , biology , paleontology , statistics , mathematics , amygdala
ApoE2 mice show acquisition and retrieval of conditioned fear but in contrast to apoE3 and apE4 mice no extinction.