Open AccessMethylphenidate improves the behavioral and cognitive deficits of neurogranin knockout mice
Author(s) -
Huang F. L.,
Huang K.P.
Publication year - 2012
Publication title -
genes, brain and behavior
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.315
H-Index - 91
eISSN - 1601-183X
pISSN - 1601-1848
DOI - 10.1111/j.1601-183x.2012.00825.x
Subject(s) - neurogranin , knockout mouse , methylphenidate , neuroscience , cognition , psychology , cognitive psychology , medicine , biology , psychiatry , attention deficit hyperactivity disorder , receptor , biochemistry , protein kinase c , enzyme
Ritalin and enrichment improve neurogranin mutant mice in cognition and behaviors. They may help Jacobsen syndrome children too. NgKO mice are impaired in social interaction. Ritalin and environmental enrichment correct such deficit.