Open AccessChanges in adult neurogenesis in neurodegenerative diseases: cause or consequence?
Author(s) -
Thompson A.,
Boekhoorn K.,
Van Dam A.M.,
Lucassen P. J.
Publication year - 2008
Publication title -
genes, brain and behavior
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.315
H-Index - 91
eISSN - 1601-183X
pISSN - 1601-1848
DOI - 10.1111/j.1601-183x.2007.00379.x
Subject(s) - neurogenesis , amyotrophic lateral sclerosis , neuroscience , disease , dementia , epilepsy , depression (economics) , medicine , frontotemporal dementia , psychology , pathology , economics , macroeconomics
This review addresses the role of adult hippocampal neurogenesis and stem cells in some of the most common neurodegenerative disorders and their related animal models. We discuss recent literature in relation to Alzheimer’s disease and dementia, Parkinson’s disease, Huntington’s disease, amyotrophic lateral sclerosis, alcoholism, ischemia, epilepsy and major depression.