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Point‐of‐care oral‐based diagnostics
Author(s) -
Hart RW,
Mauk MG,
Liu C,
Qiu X,
Thompson JA,
Chen D,
Malamud D,
Abrams WR,
Bau HH
Publication year - 2011
Publication title -
oral diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.953
H-Index - 87
eISSN - 1601-0825
pISSN - 1354-523X
DOI - 10.1111/j.1601-0825.2011.01808.x
Subject(s) - point of care testing , point of care , computer science , medical physics , patient care , medicine , intensive care medicine , pathology , nursing
Oral Diseases (2011) 17 , 745–752 Many of the target molecules that reside in blood are also present in oral fluids, albeit at lower concentrations. Oral fluids are, however, relatively easy and safe to collect without the need for specialized equipment and training. Thus, oral fluids provide convenient samples for medical diagnostics. Recent advances in lab‐on‐a‐chip technologies have made minute, fully integrated diagnostic systems practical for an assortment of point‐of‐care tests. Such systems can perform either immunoassays or molecular diagnostics outside centralized laboratories within time periods ranging from minutes to an hour. The article briefly reviews recent advances in devices for point‐of‐care testing with a focus on work that has been carried out by the authors as part of a NIH program.