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Proliferative verrucous leukoplakia: a concise update
Author(s) -
Bagan J,
Scully C,
Jimenez Y,
Martorell M
Publication year - 2010
Publication title -
oral diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.953
H-Index - 87
eISSN - 1601-0825
pISSN - 1354-523X
DOI - 10.1111/j.1601-0825.2009.01632.x
Subject(s) - leukoplakia , medicine , verrucous carcinoma , dermatology , oral leukoplakia , etiology , human papillomavirus , pathology , basal cell , cancer
Oral Diseases (2010) 16 , 328–332 Proliferative verrucous leukoplakia (PVL) is of uncertain etiology but may be associated with human papillomavirus (HPV) infection. Proliferative verrucous leukoplakia is seen mainly in older women, beginning as a simple slow‐growing, persistent leukoplakia that tends to spread and become multifocal and affect the gingival frequently. In time, PVL develops exophytic, wart‐like or erythroplakic areas that become squamous carcinomas. Proliferative verrucous leukoplakia appears to resist to all attempts at therapy and often recurs.