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Desquamative gingivitis: retrospective analysis of disease associations of a large cohort
Author(s) -
Leao JC,
Ingafou M,
Khan A,
Scully C,
Porter S
Publication year - 2008
Publication title -
oral diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.953
H-Index - 87
eISSN - 1601-0825
pISSN - 1354-523X
DOI - 10.1111/j.1601-0825.2007.01420.x
Subject(s) - pemphigus vulgaris , mucocutaneous zone , medicine , gingivitis , dermatology , bullous pemphigoid , disease , dermatomyositis , connective tissue disease , retrospective cohort study , cicatricial pemphigoid , cohort , pemphigus , leukoplakia , pemphigoid , pathology , autoimmune disease , immunology , dentistry , cancer , antibody
Background: Desquamative gingivitis (DG) is usually a manifestation of immunologically mediated mucocutaneous disorders, although it was previously suggested to be hormonally related. Methods: One hundred and eighty‐seven Caucasian UK residents with clinical features of DG (126 female, median age of 51 years, range 23–93 years) were retrospectively evaluated. Results: It was established that, in this population, the largest cohort yet reported, oral lichen planus was most common (70.5%) while mucous membrane pemphigoid (14%), pemphigus vulgaris (13%), linear IgA disease (1.6%), dermatomyositis (0.5%) and mixed connective tissue disease (0.5%) were less common. Conclusion: Oral lichen planus is the main disorder associated with DG. However, DG may be a feature of bullous disease and connective tissue disease.