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Histological and ultrastructural evaluation of bone around Bio‐Oss ® particles in sinus augmentation
Author(s) -
Orsini G,
Scarano A,
Degidi M,
Caputi S,
Iezzi G,
Piattelli A
Publication year - 2007
Publication title -
oral diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.953
H-Index - 87
eISSN - 1601-0825
pISSN - 1354-523X
DOI - 10.1111/j.1601-0825.2006.01343.x
Subject(s) - sinus (botany) , ultrastructure , transmission electron microscopy , electron microscope , materials science , medicine , biomaterial , biomedical engineering , dentistry , implant , pathology , anatomy , surgery , biology , nanotechnology , botany , physics , optics , genus
Aim: The aim of the present study was to evaluate histological and ultrastructural features of bone surrounding Bio‐Oss ® particles retrieved, in the same patient, 20 months and 7 years after sinus augmentation. Materials and Methods: A 54‐year patient who needed sinus elevation before implant rehabilitation participated in this study. Two bone cores at two different times were harvested from a Bio‐Oss ® regenerated sinus and processed for examination under light and transmission electron microscopy. Results: Under light microscopy, in the 20‐month specimen, most of the particles were surrounded by a thin layer of newly formed bone; in the 7‐year specimen there was mainly compact bone in direct contact with the particles. Under transmission electron microscopy, it was possible to characterize the bone–biomaterial interface; in the 20‐month specimen an electron‐dense layer was seen, whereas, almost no electron‐dense lines were seen at the interface in the 7‐year specimen. Conclusions: Bio‐Oss ® particles did not interfere with bone‐healing processes after sinus augmentation procedures and promoted new bone formation. This study can help clinicians to understand better the morphological characteristics of bone regeneration processes using Bio‐Oss ® after 20 months and, most importantly, after a longer time of interaction with surrounding tissues.