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Oral lichen planus: a retrospective study of 690 British patients
Author(s) -
Ingafou M,
Leao JC,
Porter SR,
Scully C
Publication year - 2006
Publication title -
oral diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.953
H-Index - 87
eISSN - 1601-0825
pISSN - 1354-523X
DOI - 10.1111/j.1601-0825.2005.01221.x
Subject(s) - oral lichen planus , medicine , oral medicine , dermatology , oral and maxillofacial pathology , medical record , reticular connective tissue , retrospective cohort study , presentation (obstetrics) , dentistry , surgery , pathology
Objective: This is the largest UK patient group with oral lichen planus (OLP) to be studied in terms of the demographic and clinical characteristics. Material and methods: Data were taken from the medical records of 690 consecutive patients referred to Oral Medicine subsequently found to have clinical, and usually histopathological confirmatory features of OLP. Over two‐thirds (68.7%) of the patients were Caucasians. Results: Eighty‐two per cent of the patients had been referred to a specialist Oral Medicine service by general dental practitioners, 62% of the patients being referred as a consequence of oral mucosal and/or gingival pain. Reticular OLP was the most common intra‐oral presentation, but 60% of such lesions were accompanied by other clinical types of OLP. 95% of lesions were bilateral. About 13% of patients reported symptoms or signs, or had a known history of lichen planus or possible lichen planus affecting non‐oral epithelia. In only 13% of patients did all signs and symptoms of OLP resolve within 12–246 months (median 35 months). A malignant transformation rate of 1.9% was observed in the present group. Conclusion: Oral lichen planus in UK persons almost always gives rise to bilateral reticular OLP, rarely resolves spontaneously, and has a low rate of malignant transformation.