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Salivary gland neoplasms in Maiduguri, north‐eastern Nigeria
Author(s) -
Otoh EC,
Johnson NW,
Olasoji H,
Danfillo IS,
Adeleke OA
Publication year - 2005
Publication title -
oral diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.953
H-Index - 87
eISSN - 1601-0825
pISSN - 1354-523X
DOI - 10.1111/j.1601-0825.2005.01137.x
Subject(s) - mucoepidermoid carcinoma , pleomorphic adenoma , medicine , malignancy , parotid gland , adenoid cystic carcinoma , carcinoma , salivary gland , cancer , pathology
Objective: To document the pattern of salivary gland neoplasia in Maiduguri, Nigeria. Design and setting: A retrospective clinical and histopathological review (January 1987–December 2002) of cases diagnosed at a tertiary care hospital. Materials and methods: Information on demographics, diagnosis and cancer management in the hospital were retrieved from biopsy reports and case notes of patients. Results: The palatal (71.9%) and parotid (78.3%) glands were the most common minor and major salivary glands involved, with a benign–malignant ratio of 1:1 and 1.4:1, respectively. Pleomorphic adenoma (44.3%) was the most common salivary gland neoplasm recorded. It was commonly reported in the third decade (mean 30.4 years) and among males (M:F, 1.4:1). Ectopic lesions (17.1%) were reported in the neck, nose and cervical nodes. Mucoepidermoid carcinoma (10.1%) was the most common salivary gland malignancy, occurring in the second and sixth decades; of equal gender distribution and predominantly in the palate (50%). The squamous cell carcinoma (10.9%) and adenoidcystic carcinoma (21.9%) were the most common malignancies in the major and minor glands respectively. There was a higher prevalence of malignancies of the parotid than previously reported for northern Nigeria ( P = 0.036). Conclusion: Pleomorphic adenoma and mucoepidermoid carcinoma were the most commonly reported benign and malignant neoplasia in this series. The prevalence of mucoepidermoid carcinoma contrasts with reported findings in other African studies.