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Accumulation of strontium and fluoride in approximal dental plaque and changes in plaque microflora after rinsing with chlorhexidine‐fluoride‐strontium solution
Author(s) -
SpetsHapponen S,
Seppa L,
Korhonen A,
Alakuijala P
Publication year - 1998
Publication title -
oral diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.953
H-Index - 87
eISSN - 1601-0825
pISSN - 1354-523X
DOI - 10.1111/j.1601-0825.1998.tb00267.x
Subject(s) - fluoride , strontium , placebo , dentistry , enamel paint , chlorhexidine , dental plaque , sodium fluoride , chemistry , dentifrice , medicine , inorganic chemistry , alternative medicine , organic chemistry , pathology
OBJECTIVES: To find out if strontium is incorporated into plaque and enamel in vivo during a 2‐week rinsing period with a chlorhexidine‐fluoride‐strontium solution and to determine the effects of the rinsing on the numbers of mutans streptococci and lactobacilli in plaque. SUBJECTS AND METHODS: A total of 18 adult participants rinsed their mouths twice a day for 2 weeks, first with a placebo solution and subsequently, separated by a I‐week interval without rinsing, with a chlorhexidine gluconate (0.05%)‐sodium fluoride (0.04%)‐strontium (100 ppm as SrCI 2 ) rinsing solution (CXFSr) for another 2 weeks. RESULTS: After the CXFSr rinsing period the strontium and fluoride contents (μg g ‐ plaque dry weight; mean ± s 1 ) of approximal plaque were 32.5 ± 4.7 and 72.8 ± 9.0, compared with the respective contents of 8.4 ± 1.2 and 42.0 ± 4.8 after placebo rinsing (P = 0.0001 for both comparisons). The strontium content remained elevated for 6 weeks. The median proportion of mutans streptococci of approximal plaque of the total viable count of bacteria was 1% after placebo rinsing but decreased to 0.2% after CXFSr rinsing. The proportion of mutans streptococci remained low at 3 weeks (P = 0.018 vs placebo) but had reached the placebo level at 6 weeks. Rinsing with CXFSr solution did not reduce lactobacilli in plaque. The strontium or fluoride contents of the enamel surfaces subjected to tooth brushing did not significantly change. CONCLUSIONS: Strontium and fluoride accumulated in dental plaque during a 2‐week CXFSr rinsing period and the proportion of mutans streptococci in approximal plaque was reduced at least for 3 weeks after completion of the rinsing.