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Analysis of oral manifestations of leukemia: a retrospective study
Author(s) -
Hou GL,
Huang JS,
Tsai CC
Publication year - 1997
Publication title -
oral diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.953
H-Index - 87
eISSN - 1601-0825
pISSN - 1354-523X
DOI - 10.1111/j.1601-0825.1997.tb00006.x
Subject(s) - medicine , leukemia , retrospective cohort study , dentistry , dermatology
OBJECTIVE: To evaluate in detail the oral complications of leukemia at initial presentation. Associations between oral manifestations and laboratory data were also investigated. STUDY DESIGN: A retrospective study of 230 cases was conducted to investigate the nature and incidence of oral manifestations at initial presentation. The following data were determined for each patient: age, sex, haemogram at diagnosis (which included haemoglobin, red blood cell counts, differential white blood cell counts, platelet counts), classification of the type of leukemia's systemic symptoms and oral manifestations at the initial physical examination including the dental consultation. RESULTS: It was revealed that the type of leukemia diagnosed, except with CML, is related to the age prediliction of patients. The incidence of leukemia is higher in males than in females. The most common manifestations of leukemia are lymphadenopathy (71.4% in ALL; 45% in AML), laryngeal pain (52.7% in ALL; 37.3% in AML), gingival bleeding (43.2% in AML; 28.6% in ALL), oral ulceration, and gingival enlargement. Fever (92.2%) was the most common symptom in patients with all types of leukemia. Platelet counts from 25000 mm ‐3 to 60000 mm ‐3 are at sufficiently low levels to result in spontaneous bleeding. Most of the patients had WBC counts of greater than 10000 mm ‐3 .Only 12.6% of patients had normal WBC counts. CONCLUSIONS: It was concluded that the age predilic‐tion and prevalence of oral manifestations are closely related to the type of leukemia.