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Chemokines and chemokine receptors: the key to understanding AIDS
Author(s) -
Thornhill MH,
Li J.
Publication year - 1997
Publication title -
oral diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.953
H-Index - 87
eISSN - 1601-0825
pISSN - 1354-523X
DOI - 10.1111/j.1601-0825.1997.tb00002.x
Subject(s) - chemokine , chemokine receptor , human immunodeficiency virus (hiv) , immunology , receptor , key (lock) , medicine , biology , disease , virology , inflammation , pathology , ecology
This article reviews the recent rapid developments in research that have demonstrated the importance of chemokines and their receptors in HIV infection and the progression to AIDS. These discoveries have transformed our understanding of how the virus may infect cells and why certain individuals may be resistant to HIV infection, and for the first time have opened up the very real prospect of developing strategies to prevent and treat this disease.