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Biocompatibility and biomineralization assessment of a new root canal sealer and root‐end filling material
Author(s) -
Cintra Luciano Tavares Angelo,
Ribeiro Thiago Alexandre Alves,
GomesFilho João Eduardo,
Bernabé Pedro Felício Estrada,
Watanabe Simone,
Facundo Aguinaldo Cândido da Silva,
Samuel Renata Oliveira,
DezanJunior Eloi
Publication year - 2013
Publication title -
dental traumatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.82
H-Index - 81
eISSN - 1600-9657
pISSN - 1600-4469
DOI - 10.1111/j.1600-9657.2012.01142.x
Subject(s) - biomineralization , biocompatibility , root canal , stain , h&e stain , connective tissue , calcium hydroxide , biocompatible material , biomedical engineering , mineralization (soil science) , chemistry , dorsum , pulpotomy , dentistry , materials science , anatomy , pulp (tooth) , pathology , staining , medicine , biology , paleontology , organic chemistry , nitrogen
Objective This study investigated the short‐term subcutaneous tissue reaction and biomineralization ability of two epoxy‐based root canal sealers containing calcium hydroxide ( MBP and MBP c) and P ro R oot MTA . Materials and methods Polyethylene tubes containing the materials were implanted into the dorsal connective tissue of W istar rats ( n = 52) for 7 or 30 days; empty implanted tubes served as controls. Specimens were stained with hematoxylin–eosin and von K ossa stain or left unstained for observation under polarized light. Qualitative and quantitative evaluations of all tissue reactions were performed. One‐way anova and the K ruskal– W allis test were used for statistical analysis ( P < 0.05). Results No significant differences were observed among the groups. All three materials induced mild‐to‐moderate tissue reactions at 7 days, which decreased over time. Dystrophic mineralization and birefringent structures were observed only in the P ro R oot MTA ® group. Conclusion Both MBP and MBP c appear to be biocompatible but do not stimulate biomineralization.