Biocompatibility and biomineralization assessment of a new root canal sealer and root‐end filling material | Zendy

Cintra Luciano Tavares Angelo | Zendy; Ribeiro Thiago Alexandre Alves | Zendy; GomesFilho João Eduardo | Zendy; Bernabé Pedro Felício Estrada | Zendy; Watanabe Simone | Zendy; Facundo Aguinaldo Cândido da Silva | Zendy; Samuel Renata Oliveira | Zendy; DezanJunior Eloi | Zendy

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Biocompatibility and biomineralization assessment of a new root canal sealer and root‐end filling material

Author(s) -

Cintra Luciano Tavares Angelo,

Ribeiro Thiago Alexandre Alves,

GomesFilho João Eduardo,

Bernabé Pedro Felício Estrada,

Watanabe Simone,

Facundo Aguinaldo Cândido da Silva,

Samuel Renata Oliveira,

DezanJunior Eloi

Publication year - 2013

Publication title -

dental traumatology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.82

H-Index - 81

eISSN - 1600-9657

pISSN - 1600-4469

DOI - 10.1111/j.1600-9657.2012.01142.x

Subject(s) - biomineralization , biocompatibility , root canal , stain , h&e stain , connective tissue , calcium hydroxide , biocompatible material , biomedical engineering , mineralization (soil science) , chemistry , dorsum , pulpotomy , dentistry , materials science , anatomy , pulp (tooth) , pathology , staining , medicine , biology , paleontology , organic chemistry , nitrogen

Objective This study investigated the short‐term subcutaneous tissue reaction and biomineralization ability of two epoxy‐based root canal sealers containing calcium hydroxide ( MBP and MBP c) and P ro R oot MTA . Materials and methods Polyethylene tubes containing the materials were implanted into the dorsal connective tissue of W istar rats ( n = 52) for 7 or 30 days; empty implanted tubes served as controls. Specimens were stained with hematoxylin–eosin and von K ossa stain or left unstained for observation under polarized light. Qualitative and quantitative evaluations of all tissue reactions were performed. One‐way anova and the K ruskal– W allis test were used for statistical analysis ( P < 0.05). Results No significant differences were observed among the groups. All three materials induced mild‐to‐moderate tissue reactions at 7 days, which decreased over time. Dystrophic mineralization and birefringent structures were observed only in the P ro R oot MTA ® group. Conclusion Both MBP and MBP c appear to be biocompatible but do not stimulate biomineralization.

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