Premium
In vitro evaluation of the cytotoxicity of calcium hydroxide‐based root canal sealers
Author(s) -
Beltes P.,
Koulaouzidou E.,
Kotoula V.,
Kortsaris A. H.
Publication year - 1995
Publication title -
dental traumatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.82
H-Index - 81
eISSN - 1600-9657
pISSN - 1600-4469
DOI - 10.1111/j.1600-9657.1995.tb00497.x
Subject(s) - cytotoxicity , calcium hydroxide , root canal , chemistry , calcium , dentistry , nuclear chemistry , in vitro , medicine , biochemistry , organic chemistry
The cytotoxicity of three calcium hydroxide‐containing root canal sealers (Sealapex, CRCS and Apexit) was tested by using L929 and BHK 21/CIS cells. After setting for 24h, the sealers were covered with cell suspension. Cytotoxicity was determined by a quantitative technique at 24h, 48h and 72h. All the sealers were found to be cytotoxic. Sealapex showed the highest cytotoxicity, causing a significant decrease in cell density. CRCS was less toxic than Sealapex and more toxic than Apexit. Apexit proved to be the least toxic material.