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Evaluation of calcium hydroxide‐containing root canal sealers with an improved rabbit ear chamber
Author(s) -
Wakabayashi H.,
Ishiguro M.,
Funato A.,
Nakamura Y.,
Matsumoto K.
Publication year - 1994
Publication title -
dental traumatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.82
H-Index - 81
eISSN - 1600-9657
pISSN - 1600-4469
DOI - 10.1111/j.1600-9657.1994.tb00077.x
Subject(s) - calcium hydroxide , calcification , connective tissue , chemistry , calcium , von kossa stain , nuclear chemistry , eugenol , biomedical engineering , materials science , dentistry , pathology , medicine , biochemistry , alkaline phosphatase , organic chemistry , enzyme
An improved rabbit ear chamber was used to evaluate calcium hydroxide‐containing root canal sealers on their potential in induce dystrophic calcification in connective tissue. Four sealers and two control materials were introduced into the chambers and the effects of these materials on the living vascular tissue were observed continuously under a biomicroscope up to 9 weeks. Conventional histopathological investigation and examinations with a scanning electron microscope and an X‐ray microanalyzer were done to supplement the results. Sealapex and Calvital (Ca(OH) 2 + iodoform) revealed almost the same tissue reaction as calcium hydroxide‐saline paste; they rapidly made a precipitate‐barrier of calcium phosphate in the connective tissue, inducing calcification. However, Dentalis KEZ(ZnO‐ca(OH) 2 + eugenol) caused mild disorders of microcirculation without calcification, as well as Canals(ZnO + eugenol). New A (Ca(OH) 2 + fatty acid) had good compatibility with micro‐vessels as well as New B(ZnO + fatty acid), however they induced no calcification and disintegrated rapidly in the tissue. These sealers were reclassified according to what they actually bring about in the tissue, not according to what they include.