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Small Intestinal Transplant Mucosal Necrosis Associated With Enteral Sodium Polystyrene Sulfonate Administration
Author(s) -
Saginur M.,
Thiesen A.,
Lacson A.,
Bigam D.,
Yap J.
Publication year - 2012
Publication title -
american journal of transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.89
H-Index - 188
eISSN - 1600-6143
pISSN - 1600-6135
DOI - 10.1111/j.1600-6143.2012.04225.x
Subject(s) - medicine , enteral administration , diarrhea , gastroenterology , parenteral nutrition , intestinal mucosa , pathology
Diarrhea is a common manifestation of disease in recipients of intestinal transplants. Sodium Polystyrene Sulfonate administration has been associated with significant bowel injury. Recognizing the diagnosis requires clinical awareness and comprehensive review of intestinal biopsies. We present an illustrative case and discussion. It is the first reported case in a pediatric intestinal transplant patient with serial intestinal biopsies documenting the evolution of disease.