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Prophylaxis, Preemption and Drug Resistance in CMV Infection: Too Little, Too Much or Just Right?
Author(s) -
Fishman J. A.
Publication year - 2012
Publication title -
american journal of transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.89
H-Index - 188
eISSN - 1600-6143
pISSN - 1600-6135
DOI - 10.1111/j.1600-6143.2011.03764.x
Subject(s) - medicine , viremia , immunology , immunosuppression , valganciclovir , viral load , cytomegalovirus , antiviral drug , viral replication , viral shedding , virology , immune system , foscarnet , neutropenia , ganciclovir , virus , human cytomegalovirus , viral disease , herpesviridae , chemotherapy
For cytomegalovirus, since the emergence of resistance to antiviral agents is associated with the host's immune status and the level of viral replication during exposure to antiviral therapy, the rate of viral resistance with induction and other newer immunosuppressive regimens merits investigation. See article by Couzi et al on page 202.