Premium
Allograft Fibrosis—Unmasking the Players at the Dance
Author(s) -
Man R. B.,
Fairchild R.
Publication year - 2010
Publication title -
american journal of transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.89
H-Index - 188
eISSN - 1600-6143
pISSN - 1600-6135
DOI - 10.1111/j.1600-6143.2009.02926.x
Subject(s) - medicine , ctgf , fibrosis , connective tissue , cytokine , effector , dance , transforming growth factor , immunology , growth factor , pathology , receptor , art , literature
New data suggest that the pleiotropic cytokine interleukin‐6 may be a key contributor to allograft fibrosis through a complex interaction with connective tissue growth factor (CTGF), a downstream effector of TGF‐beta.
See article by Booth et al on page 220.