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De Novo HLA Sensitization and Antibody Mediated Rejection Following Pregnancy in a Heart Transplant Recipient
Author(s) -
O’Boyle P. J.,
Smith J. D.,
Danskine A. J.,
Lyster H. S.,
Burke M. M.,
Banner N. R.
Publication year - 2010
Publication title -
american journal of transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.89
H-Index - 188
eISSN - 1600-6143
pISSN - 1600-6135
DOI - 10.1111/j.1600-6143.2009.02875.x
Subject(s) - medicine , human leukocyte antigen , antibody , miscarriage , heart transplantation , immunology , sensitization , pregnancy , transplantation , antigen , biology , genetics
Here we report a case wherein both donor‐specific and third‐party, paternal, HLA class II specific antibodies developed following a spontaneous miscarriage resulting in antibody‐mediated rejection in a patient who had undergone an orthotopic cardiac transplant six years earlier.