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Breaking Down Donor‐Reactive T‐Cell Activation to Two Steps
Author(s) -
Poggio E. D.,
Fairchild R. L.
Publication year - 2009
Publication title -
american journal of transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.89
H-Index - 188
eISSN - 1600-6143
pISSN - 1600-6135
DOI - 10.1111/j.1600-6143.2009.02842.x
Subject(s) - cd154 , medicine , cd8 , microbiology and biotechnology , immunology , t cell , mediator , cd40 , cytotoxic t cell , antigen , immune system , in vitro , biology , genetics
In mouse cardiac allograft recipients, donor‐reactive CD8 T cells proliferate without development to efffector function in the absence of CD154 costimulation.
See article by Shah et al on page 2697.