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Death from Metastatic Donor‐Derived Ovarian Cancer in a Male Kidney Transplant Recipient
Author(s) -
Lipshutz G. S.,
Mihara N.,
Wong R.,
Wallace W. D.,
AllenAuerbach M.,
Dorigo O.,
Rao P. N.,
Pham PC. T.,
Pham PT. T.
Publication year - 2009
Publication title -
american journal of transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.89
H-Index - 188
eISSN - 1600-6143
pISSN - 1600-6135
DOI - 10.1111/j.1600-6143.2008.02507.x
Subject(s) - medicine , malignancy , immunosuppression , transplantation , ovarian cancer , organ transplantation , kidney transplantation , malignant transformation , cancer , pathology
Posttransplant malignancy developing in an allograft is an uncommon complication of organ transplantation. The tumor may represent malignant transformation of donor or recipient cells that were previously normal, metastatic malignancy of recipient origin or malignancy transmitted from organ donor to recipient. Establishing the origin of the malignancy is critical to treatment algorithms. It is generally believed allograft removal and immunosuppression withdrawal will lead to resolution of transmitted malignancies in cases where the renal allograft is the origin. We report a male patient who developed metastatic ovarian malignancy secondary to donor transmission.